Left ventricular aneurysm in an adult patient with mucopolysaccharidosis type I: Comment on pathogenesis of a novel complication

► Primary apical LV aneurysm without evidence of ischemia in the setting of attenuated MPS I. ► Ventricular aneurysm in MPS I relates to alterations in the myocardial extracellular matrix. ► The importance of careful surveillance for cardiac lesions in MPS patients.