Positive effect of a simplified diet on blood phenylalanine control in different phenylketonuria variants, characterized by newborn BH4 loading test and PAH analysis

► Effect of a simplified diet on the course/treatment control of the PKU. ► Blood phenylalanine control is not adversely affected long term with this dietary approach. ► It introduced a pragmatic way of ensuring that patients eat enough but not excess phenylalanine intake from fruit and vegetables.