Piracetam, an AMPAkine drug, facilitates memory consolidation in the day-old chick

► Piracetam, an AMPAkine drug, is known to have nootropic properties. ► We examined piracetam's action on passive avoidance learning in day-old chicks. ► 10 mg/kg piracetam enhanced memory consolidation. ► Memory facilitation was seen with injection as late as 120 min post-training. ► A facilitatory effect of piracetam was not seen for memory reconsolidation.