Long-term naringin consumption reverses a glucose uptake defect and improves cognitive deficits in a mouse model of Alzheimer's disease

► Protection of naringin against Aβ-induced cognitive deficits in a mouse model of AD. ► Decrease in senile plaque formation by naringin treatment in a mouse model of AD. ► Reversion of a glucose uptake defect by naringin treatment in a mouse model of AD. ► Inhibition of GSK-3β activity by naringin treatment in a mouse model of AD.