Neurobehavioral toxic effects of perinatal oral exposure to aluminum on the developmental motor reflexes, learning, memory and brain neurotransmitters of mice offspring

► Perinatal Al exposure causes deficits in the sensory motor reflexes of the pups. ► Locomotor activity, learning and cognitive behaviors are affected at adolescent age. ► Neurotransmitters DA and 5-HT in the forebrain are suppressed at all postnatal ages. ► Critical perinatal period of brain development needs attention from Al toxicity.