Effects of intraplantar Nocistatin and (±)-J 113397 injections on nociceptive behavior in a rat model of inflammation

► Intraplantar Nocistatin and (±)-J 113397 prevented the nociception in inflammation. ► Functional and receptor N/OFQ antagonism prevents pain behavior. ► N/OFQ is involved in pain induced by carrageenan inflammation in rats.