Intraplantar injection of bergamot essential oil induces peripheral antinociception mediated by opioid mechanism

► BEO-induced antinociceptive may be mediated through peripheral opioid receptors. ► Linalool-induced antinociceptive may be mediated through peripheral opioid receptors. ► Antinociception induced by morphine was enhanced by the combined injection of BEO. ► Antinociception induced by morphine was enhanced by the combined injection of linalool.