کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1083953 951041 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Malnutrition was associated with poor quality of life in colorectal cancer: a retrospective analysis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی سیاست های بهداشت و سلامت عمومی
پیش نمایش صفحه اول مقاله
Malnutrition was associated with poor quality of life in colorectal cancer: a retrospective analysis
چکیده انگلیسی

Background and ObjectiveMalnutrition is a significant cause of morbidity and mortality in advanced colorectal cancer, and little is known about its relationship with quality of life (QoL). We investigated the relationship between nutritional status and QoL in colorectal cancer.MethodsWe examined a case series of 58 stage III–IV colorectal cancer patients treated at Cancer Treatment Centers of America®. Nutritional status was evaluated using laboratory measures of serum albumin, prealbumin, and transferrin, subjective global assessment (SGA) and bioelectrical impedance analysis. QoL was evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (QLQ-C30).ResultsThe prevalence of malnutrition, as determined by SGA, was 41% (24 of 58). Well-nourished patients had statistically significantly better QoL scores on the global, physical, and role functions compared to malnourished patients. Interestingly, the median role function score in well-nourished patients was 41.6 points higher than the corresponding score in malnourished patients, indicating a “much better” functioning from a patient's perspective. Similarly, QoL scores on multiple symptom scales were statistically significantly better among well-nourished patients.ConclusionThis study suggests that malnutrition is associated with poor QoL, as measured by the QLQ-C30 in colorectal cancer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Epidemiology - Volume 59, Issue 7, July 2006, Pages 704–709
نویسندگان
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