کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10882026 | 1077946 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Osmotic and diffusive properties of intracellular water in camel erythrocytes: Effect of hemoglobin crowdedness
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیوفیزیک
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Osmotic and diffusive properties of intracellular water in camel erythrocytes: Effect of hemoglobin crowdedness Osmotic and diffusive properties of intracellular water in camel erythrocytes: Effect of hemoglobin crowdedness](/preview/png/10882026.png)
چکیده انگلیسی
The amount of osmotically inactive water is 2-fold greater in camel hemoglobin solution in vitro compared to that of human, but water diffusion does not differ in camel and human hemoglobin solutions. However, the evaluation of water diffusion by magnetic resonance measurements in camel erythrocytes revealed â¼15% lower apparent diffusion coefficient (ADC) compared with human erythrocytes. When human erythrocytes were dehydrated to the level of camel erythrocytes, their osmotic and water diffusion properties were similar. These results show that a lower ADC is associated with a more pronounced increase in osmotically inactive water fraction. It is proposed that increased hemoglobin hydrophilicity allows not only augmented water-binding, but also a closer hemoglobin packaging in vivo, which in turn is associated with slower ADC and increased osmotic resistance.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cell Biology International - Volume 29, Issue 9, September 2005, Pages 731-736
Journal: Cell Biology International - Volume 29, Issue 9, September 2005, Pages 731-736
نویسندگان
Peter Bogner, Attila Miseta, Zoltan Berente, Attila Schwarcz, Gyula Kotek, Imre Repa,