Boosting of nonspecific host response by aromatic spices turmeric and ginger in immunocompromised mice

► CCl4 imparted immunosuppressed condition in male albino mice. ► Curcuma longa and Zingiber officinale boosts non specific host response in immunosuppressed mice. ► Polar compounds of C. longa and Z. officinale augments immunosuppressed macrophage function. ► C. longa and Z. officinale potentiates the non-specific host defenses against opportunistic infections. ► C. longa and Z. officinale upregulates the serum level of TNF-α and IFN-γ in CCl4 intoxicated mice.