The function of FGF signaling in the lens placode

► Previous studies suggested that FGF signaling is important for lens formation. ► We conditionally deleted FGF receptors to test the role of FGFs in lens induction. ► Fgfr1/2 deletion greatly increased cell death at the onset of lens induction. ► Pax6 and other lens cell markers were not reduced in the lens placode. ► FGF signaling is important for lens cell survival, but not for lens induction.