Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

► The pathogenesis of doxorubicin-induced cardiotoxicity is complex and multifactorial. ► Oxidative stress is a major cause of doxorubicin-induced cardiotoxicity. ► Doxorubicin-induced heart failure can appear very late after the last administration. ► There is no specific curative or preventive treatment available.