The influence and the mechanism of docosahexaenoic acid on a mouse model of Parkinson's disease

► DHA treatment significantly diminished cell death in MPTP treated mice. ► DHA did not improve decreased motor activity observed in experimental PD. ► Brain TBARS level increased in MPTP group compared to control group. ► Brain TBARS level exhibited a decrease tendency in MPTP+DHA group compared to MPTP. ► Brain SOD activity level decreased following MPTP treatment.