Caveolin-1 inhibits oligodendroglial differentiation of neural stem/progenitor cells through modulating β-catenin expression

► Caveolin-1 KO mice had increased oligodendroglial differentiation but decreased β-catenin expression. ► Caveolin-1 peptide inhibited oligodendroglial formation and up-regulated β-catenin. ► Caveolin-1 knockdown promoted oligodendroglial differentiation and down-regulated β-catenin.