دانلود مقالات ISI درباره گالکسی + ترجمه فارسی

تغییرات وابسته به سن در اسفنگیلیپید حاوی اسید نئورونی در هیپوکامپ موش

Age-dependent changes in nervonic acid-containing sphingolipids in mouse hippocampus

Keywords: گالکسی; AD; Alzheimer's disease; PD; Parkinson's disease; SPT; serine palmitoyltransferase; TFA; trifluoroacetic acid; LC/MS; liquid chromatography/mass spectrometry; UPLC; ultra-performance liquid chromatography; TQ-MS; triple quadrupole mass spectrometer; ESI;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

درمان های در حال ظهور برای اختلالات ذخیره سازی لیزوزومی نوروپاتی

Emerging therapies for neuropathic lysosomal storage disorders

Keywords: گالکسی; LSD; lysosomal storage disease; CNS; central nervous system; BBB; blood-brain barrier; ERT; enzyme replacement therapy; GAG; glycosaminoglycans; CSF; cerebrospinal fluid; FDA; food and drug administration; ICV; intracerebroventricular; HLA; human leukocyt

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2017 سفارش ترجمه

اصول پایه عصب شناسی درجه های جداسازی: روش های تجربی برای جداسازی سلول های آستروگلالی و الیگوندرگلالیال و هدف گیری ژنتیکی

Basic NeuroscienceFinding degrees of separation: Experimental approaches for astroglial and oligodendroglial cell isolation and genetic targeting

Keywords: گالکسی; GalC; galactocerebroside; FACS; fluorescence-activated cell sorting; BAC; bacterial artificial chromosome; PAC; P1 artificial chromosome; EGFP; enhanced green fluorescent protein; Aqp4; aquoporin4; Apoe4; apolipoprotein E4; Blbp; brain lipid binding prote

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2014 سفارش ترجمه

کاهش وابستگی زمان به خواص نوروتروفیک پیوند های سلول های بنیادی عصبی آنها را وابسته به حمایت محیطی ویژه مغز می کند

Time associated decline in neurotrophic properties of neural stem cell grafts render them dependent on brain region-specific environmental support

Keywords: گالکسی; NPCs; neural precursor cells; GFAP; glial fibrillary acidic protein; GFP; green fluorescent protein; FGF2; fibroblast growth factor 2; 6-OH DA; 6-hydroxydopamine; BrdU; bromodeoxyuridine; GalC; galactocerebroside; PSA-NCAM; Polysialylated-neural cell adhe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

گزارش تحقیقاتی غربالگری با توان بالا در درمان سلول های بنیادی برای لوسییدوستروفیزاسیون سلول های گلبولی با استفاده از نوروفنوتیپی اتوماتیک موش های مشکوک

Research ReportHigh-throughput screening of stem cell therapy for globoid cell leukodystrophy using automated neurophenotyping of twitcher mice

Keywords: گالکسی; Globoid cell leukodystrophy; Noldus technology; EthoVision XT7; Behavioral phenotype; Twitcher mouse; Mesenchymal stem/stromal cells; GLD; globoid cell leukodystrophy; MSC; mesenchymal stromal cell; GALC; galactosylceramidase; BMT; bone marrow transplant;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

ژن درمانی بر اساس تقاضا: تنظیم ژن درمانی خاص

Gene therapy on demand: Site specific regulation of gene therapy

Keywords: گالکسی; ARE; antioxidant response element; BVR; biliverdin reductase; CD; cytosine deaminase; DBD; DNA binding domain; Epo; erythropoietin; 5-FC; 5-fluorocytosine; GALC; galactocerebrosidase; HIF; hypoxia inducible factor; HO-1; heme oxygenase-1; HRE; hypoxia res

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2013 سفارش ترجمه

New in vitro model derived from brain-specific Mut-/- mice confirms cerebral ammonium accumulation in methylmalonic aciduria

Keywords: گالکسی; 2-MCA; 2-methylcitrate; AKG; α-ketoglutarate; BBB; blood-brain barrier; CSF; cerebrospinal fluid; CNS; central nervous system; cTIN; chronic tubulointerstitial nephritis; DIV; day in vitro; FGF; fibroblast growth factor; GalC; galactocerebroside; GDH; gl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Oligodendrogliopathy in neurodegenerative diseases with abnormal protein aggregates: The forgotten partner

Keywords: گالکسی; 5-HT; 5-hydroxytryptamine; Aβ; β-amyloid; ABCA8; ATP binding cassette subfamily A member 8; AD; Alzheimer's disease; ADP; adenosine diphosphate; AGD; argyrophilic grain disease; ALS; amyotrophic lateral sclerosis; AMBRA-1; autophagy and beclin 1 regul

دانلود رایگان متن کامل مقاله ISI 131 صفحه سال انتشار : 2018 سفارش ترجمه

Properties, metabolism and roles of sulfogalactosylglycerolipid in male reproduction

Keywords: گالکسی; Sulfogalactosylglycerolipid; Seminolipid; Lipidomics; Mass spectrometry; Lipid rafts; Male reproduction; Male fertility; APMs; anterior head plasma membrane vesicles; ARSA; arylsulfatase A; CGT; ceramide galactosyltransferase; CHO; Chinese hamster ovary c

دانلود رایگان متن کامل مقاله ISI 139 صفحه سال انتشار : 2018 سفارش ترجمه

Original articleLate onset Krabbe disease due to the new GALC p.Ala543Pro mutation, with intriguingly high residual GALC activity in vitro

Keywords: گالکسی; Galactosylceramide degradation; Late onset Krabbe disease; Mutation introducing proline; Residual GALC activity; Skin ultrastructure; Specific inclusions; GAC; galactosylceramide; GALC; galactosylceramidase; KD; Krabbe disease; LOKD; late-onset Krabbe dis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Immunolocalization of glutaryl-CoA dehydrogenase (GCDH) in adult and embryonic rat brain and peripheral tissues

Keywords: گالکسی; 1H-MRS; proton magnetic resonance spectroscopy; 3-OHGA; 3-hydroxyglutaric acid; BBB; blood brain barrier; BSA; bovine serum albumin; CNS; central nervous system; DEPC; diethyl-pyrocarbonate; GA; glutaric acid; GA-I; glutaric aciduria type I; GalC; galacto

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Optogenetic control of cell differentiation in channelrhodopsin-2-expressing OS3, a bipotential glial progenitor cell line

Keywords: گالکسی; Differentiation; Oligodendrocyte; PI3K/Akt signaling; Intracellular ion environment; Channelrhodopsin-2; Photo-activation; ChR2; Channelrhodopsin-2; BL; blue light; OS3ChR2 cells; ChR2-expressing OS3 cells; GalC; galactocerebrosides; GFAP; glial fibrillar

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Pilot study of newborn screening for six lysosomal storage diseases using Tandem Mass Spectrometry

Keywords: گالکسی; DBS; Dried blood spot on a newborn screening card; GAA; Acid α-glucosidase; GALC; Galactocerebrosidase; GBA; Glucocerebrosidase; GLA; α-Galactosidase A; IDUA; α-Iduronidase; MPS-I; Mucopolysaccharidosis-I; MS/MS; Tandem mass spectrometry; MRM; Multiple

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Ammonium accumulation is a primary effect of 2-methylcitrate exposure in an in vitro model for brain damage in methylmalonic aciduria

Keywords: گالکسی; 2-MCA; 2-methylcitrate; CNS; central nervous system; DIV; day in vitro; DMSO; dimethyl sulfoxyde; GalC; galactocerebroside; GDH; glutamate dehydrogenase; GFAP; glial fibrillary acidic protein; GS; glutamine synthetase; HRP; horseradish peroxidase; LC3; mi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Intravenous injection of AAVrh10-GALC after the neonatal period in twitcher mice results in significant expression in the central and peripheral nervous systems and improvement of clinical features

Keywords: گالکسی; GLD; Globoid cell leukodystrophy; GALC; Galactocerebrosidase; twi; Twitcher; PND; Post-natal day; CNS; Central nervous system; PNS; Peripheral nervous system; HSCT; Hematopoietic stem cell transplantation; MLD; Metachromatic leukodystrophy; LFB/PAS; Luxol

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Regular ArticleEnzyme replacement therapy of a novel humanized mouse model of globoid cell leukodystrophy

Keywords: گالکسی; AAV; adeno-associated virus; CNS; central nervous system; ERT; enzyme replacement therapy; ES; embryonic stem (cell); GALC; galactosylceramidase; G-CSF; granulocyte colony-stimulating factor; GFAP; glial fibrillary acidic protein; GLD; globoid cell leukod

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Disease specific therapies in leukodystrophies and leukoencephalopathies

Keywords: گالکسی; X-ALD; X-linked Adrenoleukodystrophy; AGS; Aicardi-Goutières Syndrome; CSF; cerebrospinal fluid; IFNα; α-interferon; RNA; ribonucleic acid; DNA; deoxyribonucleic acid; SLE; systemic lupus erythematosus; AxD; Alexander disease; GFAP; growth factor ass

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Pharmacological chaperones increase residual β-galactocerebrosidase activity in fibroblasts from Krabbe patients

Keywords: گالکسی; GALC; β-galactocerebrosidase; GLD; globoid cell leukodistrophy; ERT; enzyme replacement therapy; CNS; central nervous system; PNS; peripheral nervous system; LSDs; lysosomal storage diseases; Krabbe disease; Pharmacological chaperones; Missense mutations

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Late-onset Krabbe disease is predominant in Japan and its mutant precursor protein undergoes more effective processing than the infantile-onset form

Keywords: گالکسی; ASA; solvent-accessible surface area; BMT; bone marrow transplantation; GALC; galactocerebrosidase; GalCer; galactocerebroside; HM-gal; 6-hexadecanoylamino-4-methylumbelliferyl-β-d-galactopyranoside; RMSD; root-mean-square distance; TIM; central trioseph

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Neurorescue effects and stem properties of chorionic villi and amniotic progenitor cells

Keywords: گالکسی; ANG-2; angiopoietin-2; BDNF; brain-derived neurotrophic factor; ChAT; cholin acetyltransferase; CM; conditioned medium; DAPI; 4′-6-diamidino-2-phenylindole; DAT; dopamine N acetyltransferase; DCX; double cortin; ELISA; enzyme-linked immunosorbent assay;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

IFN-γ-induced apoptosis of human embryonic stem cell derived oligodendrocyte progenitor cells is restricted by CXCR2 signaling

Keywords: گالکسی; OPC; oligodendrocyte progenitor cell; hESC; human embryonic stem cell; CXCL10; CXC chemokine ligand 10; MS; multiple sclerosis; SCI; spinal cord injury; JHMV; mouse hepatitis virus; RA; retinoic acid; GRM; glial restrictive media; EGF; epidermal growth fa

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Psychosine induces the dephosphorylation of neurofilaments by deregulation of PP1 and PP2A phosphatases

Keywords: گالکسی; GALC; galactosyl-ceramidase; NF; neurofilament; NFL; neurofilament light polypeptide; NFM; neurofilament medium polypeptide; NFH; neurofilament heavy polypeptide; PP1; protein phosphatase 1; PP2A; protein phosphatase 2A; TEM; transmission electron microsc

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Regulation of remyelination in multiple sclerosis

Keywords: گالکسی; Remyelination; Oligodendrocytes; Hyaluronan; Wnt; Notch1; Retinoid X receptor; 15d-PGJ(2); 15-deoxy-Δ12,14-prostaglandin J2; CNP; 2′,3′-cyclic nucleotide 3′-phosphodiesterase; CNS; central nervous system; cKO; conditional knockout; dpl; days post l

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Caveolin-1 inhibits oligodendroglial differentiation of neural stem/progenitor cells through modulating β-catenin expression

Keywords: گالکسی; Cav-1; caveolin-1; Cav-1 KO mice; caveolin-1 knockout mice; NPCs; neural progenitor cells; GalC; galactocerebroside; CNPase; 2′,3′-cyclic nucleotide 3′-phosphodiesterase; siRNA; small interfering RNA; Con P; Cav-1 scrambled control peptide; Cav P; C

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Implementation of newborn screening for Krabbe disease: Population study and cutoff determination

Keywords: گالکسی; Newborn screening; Tandem mass spectrometry; GALC; Krabbe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Differential expression of five members of the ADAM family in the developing chicken brain

Keywords: گالکسی; in situ hybridization; blood vessel; pineal gland; choroid plexus; neuroepithelium; oligodendrocytes; ADAM; a disintegrin and metalloprotease; E; embryonic day; EGF; epidermal growth factor; Galc; galactocerebroside; HBSS; Hepes-buffered salt solution; OR

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2008 سفارش ترجمه

A novel oligodendrocyte cell line OLP6 shows the successive stages of oligodendrocyte development: Late progenitor, immature and mature stages

Keywords: گالکسی; Edg-2/LPA1; lysophosphatidic acid; myelination; oligodendrocyte cell line; survival; temperature-sensitive simian virus 40 T-antigen; CNPase; 2′-3′-cyclic-nucleotide 3′-phosphodiesterase; Edg-2/LPA1; endothelial differentiation gene receptor-2; FBS;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Antibody responses against galactocerebroside are potential stage-specific biomarkers in multiple sclerosis

Keywords: گالکسی; Galactocerebroside; myelin antigens; autoantibody; multiple sclerosis; experimental allergic encephalomyelitis; AM; Acute monophasic; CIS; Clinically isolated syndrome; CNS; Central nervous system; EAE; Experimental allergic encephalomyelitis; GalC; Galac

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Heredofamilial Brain Calcinosis Syndrome

Keywords: گالکسی; AHO; Albright hereditary osteodystrophy; APS; autoimmune polyglandular syndrome; BCS; brain calcinosis syndrome; COFS; cerebrooculo-facio-skeletal; CS; Cockayne syndrome; CT; computed tomography; DHPR; dihydropteridine reductase; GALC; galactocerebrosidas

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Progesterone increases oligodendroglial cell proliferation in rat cerebellar slice cultures

Keywords: گالکسی; progesterone; oligodendrocytes; microglial cells; cerebellum; DIV; days in vitro; GalC; galactocerebroside; GFAP; glial fibrillary acidic protein; MAP-2; microtubule-associated protein-2; MBP; myelin basic protein; NeuN; neuronal nuclei; OPC; oligodendroc

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه