Short-term alterations in hippocampal glutamate transport system caused by one-single neonatal seizure episode: Implications on behavioral performance in adulthood

► Neonatal seizures cause alterations in hippocampal glutamate uptake. ► Neonatal seizures modulate glutamate transporters content. ► Increase in GFAP-positive cells are found 24 h after seizure. ► Neonatal seizure cause long-term behavioral alterations.