Design and synthesis of tetrahydropyridopyrimidine based Toll-Like Receptor (TLR) 7/8 dual agonists

Design and synthesis of tetrahydropyridopyrimidine based Toll-Like Receptor (TLR) 7/8 dual agonists

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 28, Issue 19, 15 October 2018, Pages 3216-3221

David C. McGowan, Florence Herschke, Mourad D. Khamlichi, Mari Luz Rosauro, Sara M. Pérez Benedicto, Frederik Pauwels, Bart Stoops, Vineet Pande, Annick Scholliers, Bertrand Van Schoubroeck, Wendy Mostmans, Kris Van Dijck, Tine Thoné, Helen Horton,