کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
11017859 | 1720566 | 2018 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Normal Aging Slows Spontaneous Switching in Auditory and Visual Bistability
ترجمه فارسی عنوان
پیری طبیعی به طور خودکار تغییر در شنوایی و بایستی بصری را به خود می گیرد
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کلمات کلیدی
ACCPFCMRSAwareness - آگاهیγ-aminobutyric acid - اسید γ-آمینوبوتیریکScene analysis - تجزیه و تحلیل صحنهanalysis of variance - تحلیل واریانسANOVA - تحلیل واریانس Analysis of varianceAttention - توجهPerceptual organization - سازمان ادراکیAge - سنmagnetic resonance spectroscopy - طیف سنجی رزونانس مغناطیسیprefrontal cortex - قشر prefrontalanterior cingulate cortex - قشر سینگولیت قدامی، کورتکس سینگولیت قدامیAuditory Cortex - قشر شنواییGABA - گابا
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
چکیده انگلیسی
Age-related changes in auditory and visual perception have an impact on the quality of life. It has been debated how perceptual organization is influenced by advancing age. From the neurochemical perspective, we investigated age effects on auditory and visual bistability. In perceptual bistability, a sequence of sensory inputs induces spontaneous switching between different perceptual objects. We used different modality tasks of auditory streaming and visual plaids. Young and middle-aged participants (20-60 years) were instructed to indicate by a button press whenever their perception changed from one stable state to the other. The number of perceptual switches decreased with participants' ages. We employed magnetic resonance spectroscopy to measure non-invasively concentrations of the inhibitory neurotransmitter (γ-aminobutyric acid, GABA) in the brain regions of interest. When participants were asked to voluntarily modulate their perception, the amount of effective volitional control was positively correlated with the GABA concentration in the auditory and motion-sensitive areas corresponding to each sensory modality. However, no correlation was found in the prefrontal cortex and anterior cingulate cortex. In addition, effective volitional control was reduced with advancing age. Our results suggest that sequential scene analysis in auditory and visual domains is influenced by both age-related and neurochemical factors.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 389, 1 October 2018, Pages 152-160
Journal: Neuroscience - Volume 389, 1 October 2018, Pages 152-160
نویسندگان
Hirohito M. Kondo, Takanori Kochiyama,