A method to quantify intracellular glycation in dermal fibroblasts using liquid chromatography coupled to fluorescence detection - Application to the selection of deglycation compounds of dermatological interest

As an application, a screening of natural extracts have been done and the method allowed identifying extracts able to significantly reduce the amount of pentosidine in fibroblasts (−32%). These extracts act as deglycation agents of interest in the field of dermatology and cosmetology.