کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
11263960 | 1544896 | 2018 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Computational analysis of micro RNAs compatibility in pharmacogenomic based regulatory networks of psoriatic arthritis: An initiation towards identifying a potential miRNA to treat psoriatic arthritis
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم کشاورزی و بیولوژیک (عمومی)
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چکیده انگلیسی
In the era of post genomics, performing a computational analysis to understand the pharmacogenomic based regulation in Psoriatic Arthritis with respect to the principles of data mining and constructing a regulatory network with respect to the principles of systems biology and analyzing the network with respect to the principles of test statistic remains a challenging task to execute. The challenge was approached by identifying the associated genes of Psoriatic Arthritis from PharmGKB and it was followed by identifying the associated regulators (MicroRNAs and Transcription Factors) from miRTarBase/RegNetworks. Finally the compatibility of miRNA in Regulatory Networks is analyzed by the statistical measure in miRmap.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biocatalysis and Agricultural Biotechnology - Volume 16, October 2018, Pages 545-547
Journal: Biocatalysis and Agricultural Biotechnology - Volume 16, October 2018, Pages 545-547
نویسندگان
Harishchander Anandaram, Daniel Alex Anand,