کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1148223 | 957825 | 2008 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Estimation using non-central hypergeometric distributions in combining 2Ã2 tables
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
ریاضیات
ریاضیات کاربردی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
We consider estimation of the overall log odds ratio and the between-study variance or heterogeneity variance from a series of independent 2Ã2 tables. The estimates are obtained using the conditional distributions of the tables with fixed marginal totals, specifically the non-central hypergeometric distribution, along with an assumed normal distribution of the true study-specific log odds ratios. The method presented differs from the traditional random effects meta-analysis approach for 2Ã2 tables in two respects. First, it does not assume a normal distribution for the observed within-study log odds ratio statistics; and second, it does not require estimation of the heterogeneity variance as a first step for estimation of the overall log odds ratio. Furthermore, the method directly provides an estimate of the heterogeneity variance and an associated standard error. Several real examples are discussed to illustrate the approach outlined in this paper, and to compare it with other common approaches.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Statistical Planning and Inference - Volume 138, Issue 12, 1 December 2008, Pages 3993-4005
Journal: Journal of Statistical Planning and Inference - Volume 138, Issue 12, 1 December 2008, Pages 3993-4005
نویسندگان
Kurex Sidik, Jeffrey N. Jonkman,