کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1185507 963408 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Structural characterisation of polysaccharides from Tricholoma matsutake and their antioxidant and antitumour activities
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Structural characterisation of polysaccharides from Tricholoma matsutake and their antioxidant and antitumour activities
چکیده انگلیسی

In this study, polysaccharides from Tricholoma matsutake (TM-P) were purified using a DEAE-Sepharose fast flow column and three polysaccharide fractions (TM-P1, TM-P2 and TM-P3) were obtained. The chemical composition and structural characteristics of TM-P2 were quite different from those of TM-P1 and TM-P3. TM-P2 consisted of glucose, galactose and mannose with a molar ratio of 5.9:1.1:1.0. The glycosidic linkages were mainly composed of 1,6- and 1-linked glucose. Furthermore, TM-P2 showed the strongest in vitro antioxidant and antitumour activities. The oxygen radical absorbance capacity (ORAC) of TM-P2 was 2100.44 μmol Trolox/g. The antiproliferative activities of TM-P2 (4.0 mg/ml) on the growth of HepG2 and A549 cells were 67.98% and 59.04%, respectively.


► Three polysaccharide fractions obtained from T. matsutake were purified.
► The chemical composition and structure characteristics were determined.
► The antiproliferative activities on HepG2 and A549 cells were also evaluated.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 138, Issue 4, 15 June 2013, Pages 2242–2249
نویسندگان
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