کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1185853 | 963414 | 2009 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Beneficial effects of fucoidan on osteoblastic MG-63 cell differentiation
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Beneficial effects of fucoidan on osteoblastic MG-63 cell differentiation Beneficial effects of fucoidan on osteoblastic MG-63 cell differentiation](/preview/png/1185853.png)
چکیده انگلیسی
Fucoidan extracted from the marine brown alga Undaria pinnatifida, significantly induced osteoblastic cell differentiation. Our results indicated that a non-toxic sulphated polysaccharide, fucoidan, can increase activity of alkaline phosphatase (ALP) and level of osteocalcin (OC) as phenotypic markers for early-stage osteoblastic differentiation and terminally osteoblastic differentiation, respectively. Furthermore, the results showed positive effects of fucoidan on bone morphogenic protein-2 (BMP-2) as an important factor for bone formation, remodeling and mineralization. The present study may provide new insights in the osteoblastic differentiation of fucoidan and possibility for its application in bone health supplement.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 116, Issue 4, 15 October 2009, Pages 990–994
Journal: Food Chemistry - Volume 116, Issue 4, 15 October 2009, Pages 990–994
نویسندگان
Young-Sook Cho, Won-Kyo Jung, Jung-Ae Kim, IL-Whan Choi, Se-Kwon Kim,