کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1215939 966988 2007 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Process analytics for purification of monoclonal antibodies
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Process analytics for purification of monoclonal antibodies
چکیده انگلیسی

The application of appropriate analytical methods is an essential requirement for the purification of therapeutic antibodies. A range of analytical methods need to be employed to effectively determine the purity, identity, integrity and activity of these important class of pharmaceuticals. These include notably electrophoresis, high performance liquid chromatography and immunoassays. Regulatory and industry demands in recent years have brought the need for improvements and many have been successfully implemented. This article reviews the current analytical methods applied to support the purification of monoclonal antibodies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography B - Volume 848, Issue 1, 15 March 2007, Pages 79–87
نویسندگان
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