کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1216515 967018 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Rapid GC–MS analysis of methamphetamine and its metabolites in urine—application of a short narrow-bore capillary column to GC–MS
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Rapid GC–MS analysis of methamphetamine and its metabolites in urine—application of a short narrow-bore capillary column to GC–MS
چکیده انگلیسی

A rapid analysis of methamphetamine and its metabolites in urine was performed by gas chromatography–mass spectrometry (GC–MS) using a short narrow-bore capillary column (NBC) (5 m × 0.1 mm I.D.). For detection, selected ion monitoring (SIM) was performed for the characteristic ions of each of the compounds. The analytes were independently detected within 2 min. Linearity was demonstrated over a range from 25–2500 ng/ml. As an application of this study, a urine sample from a drug-abuse suspect was analyzed. The analytes from the actual sample were detected with reasonable reproducibility. The results indicate the possibility of rapid analysis using a conventional GC–MS with a short NBC at a relatively low inlet pressure.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography B - Volume 842, Issue 2, 2 October 2006, Pages 116–120
نویسندگان
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