کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1217292 967083 2011 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Simultaneous analysis of synthetic musks and triclosan in human breast milk by gas chromatography tandem mass spectrometry
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Simultaneous analysis of synthetic musks and triclosan in human breast milk by gas chromatography tandem mass spectrometry
چکیده انگلیسی

A comprehensive method was developed for the simultaneous analysis in human breast milk of 12 synthetic musks, five nitro musks, six polycyclic muks and one macrocyclic musk; as well as one musk metabolite and triclosan. The target analytes were freeze dried and extracted using the accelerated solvent extraction (ASE) procedure. The extracts were further purified by gel permeation chromatography (GPC) and florisil solid-phase extraction (SPE) and then analyzed by gas chromatography tandem mass spectrometry (GC–MS/MS). Recoveries of the analytes based on the isotopic internal standard correction ranged from 82.4% to 112%, with relative standard derivations less than 20%. The method quantification limits (MQLs) were 0.6–5.4 ng/g lipid. The analytes were detected in human breast milk samples and ranged from 11.7 to 308.6 ng/g lipid.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography B - Volume 879, Issue 21, 1 July 2011, Pages 1861–1869
نویسندگان
, , , , , , , ,