کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1217410 967095 2006 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Comparative proteomics and immunoproteomics of Helicobacter pylori related to different gastric pathologies
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Comparative proteomics and immunoproteomics of Helicobacter pylori related to different gastric pathologies
چکیده انگلیسی

Helicobacter pylori is a Gram-negative bacterium which causes ulcer, atrophic gastritis, adenocarcinoma, or mucosa-associated lymphoid tissue lymphoma. A comparative proteomic and immunoproteomic analysis was chosen to identify the antigenic patterns of three different H. pylori strains. These strains were probed against single sera from H. pylori-positive patients affected by gastric adenocarcinoma or duodenal ulcer. We found a quite heterogeneous antigenic pattern, both from strain and sera points of view, thus underlying both a strain- and a host-specificity. The different antigenic repertoires introduced the importance of the strain to be used for immunoblotting as a diagnostic test.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography B - Volume 833, Issue 1, 20 March 2006, Pages 63–79
نویسندگان
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