کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1217468 | 1494193 | 2006 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: The salicylate trapping method: Is oxidation of salicylic acid solution oxygen and time dependent and metal catalysed? The salicylate trapping method: Is oxidation of salicylic acid solution oxygen and time dependent and metal catalysed?](/preview/png/1217468.png)
For a microdialytic trapping method we systematically investigated changes in concentrations of 2,5-dihydroxy-benzoic acid (2,5-DHBA) and 2,3-dihydroxy-benzoic acid (2,3-DHBA) in freshly prepared solutions of salicylic acid (SA). The solvent was 0.9% saline exposed to different atmospheric concentrations of oxygen (0, 21, and 100%). The solutions were treated by freezing–thawing and an ultrasonic bath in presence and absence of aluminium foil. Without aluminium the concentrations of 2,5-DHBA and 2,3-DHBA kept constant over an observed period of 160 min on different levels from below 20 ng/ml to about 100 ng/ml. In presence of aluminium the concentrations increased to maximum 307 ng/ml after 160 min. Ultrasonic irradiation amplified this effect to maximum 341 ng/ml. HPLC/ECD processing and quantitative analysis of dihydroxy-benzoic acids (DHBAs) in microdialysis may be artificially influenced by varying oxygen environment and metal catalysis.
Journal: Journal of Chromatography B - Volume 831, Issues 1–2, 2 February 2006, Pages 320–323