Synthesis, characterization and biological studies of a charge transfer complex: 2-Aminopyridinium-4-methylbenzenesulfonate

• The single crystals were grown via solution growth technique at room temperature.
• The charge transfer complex is characterized through elemental, IR, UV–vis spectra and thermal analysis.
• DNA-binding studies of CT complex have been performed.
• The CT complex is also screened for its antioxidant activity.

A single crystal charge transfer (CT) complex, 2-aminopyridinium-4-methylbenzenesulfonate (APTS) was synthesized and recrystallized by slow solvent evaporation solution growth method at room temperature. The complex has been characterized with the elemental analysis, UV–visible, infrared (IR), 1H and 13C nuclear magnetic resonance (NMR) spectra. Thermogravimetric (TG) and differential thermal analysis (DTA) were reported the thermal behaviour of the complex. Single crystal XRD studies showed that the orthorhombic nature of the crystal with space group Pbca. The biological activities of CT complex, such as DNA binding and antioxidant activity has been carried out. The results indicated that the compound could interact with DNA through intercalation and show significant capacity of scavenging with 2,2-diphenyl-2-picryl-hydrazyl (DPPH).

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