کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1230742 | 1495256 | 2013 | 12 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Solvent-free synthesis, spectral correlations and antimicrobial activities of some aryl E 2-propen-1-ones Solvent-free synthesis, spectral correlations and antimicrobial activities of some aryl E 2-propen-1-ones](/preview/png/1230742.png)
• Green aldol condensation gives more than 85% yield of a series of E 2-propen-1-ones.
• These aryl E 2-propen-1-ones were characterized by their analytical and spectral data.
• Hammett spectral linearity has been studied for 4′-iodophenyl chalcones.
• Antimicrobial activities of 4′-iodophenyl chalcones have also been studied.
Totally 38 aryl E 2-propen-1-ones including nine substituted styryl 4-iodophenyl ketones have been synthesised using solvent-free SiO2–H3PO4 catalyzed Aldol condensation between respective methyl ketones and substituted benzaldehydes under microwave irradiation. The yields of the ketones are more than 80%. The synthesised chalcones were characterized by their analytical, physical and spectroscopic data. The spectral frequencies of synthesised substituted styryl 4-iodophenyl ketones have been correlated with Hammett substituent constants, F and R parameters using single and multi-linear regression analysis. The antimicrobial activities of 4-iodophenyl chalcones have been studied using Bauer–Kirby method.
Figure optionsDownload as PowerPoint slide
Journal: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy - Volume 112, August 2013, Pages 245–256