Fluorescent sensor based on a novel conjugated polyfluorene derivative

A novel water-soluble polyfluorene derivative, poly[(9,9-bis(3′-((N,N-dimethylamino)N-ethylammonium)propyl)-2,7-fluorene)-alt-2,7-(9,9-p-divinylbenzene)]dibromide (P-2) was synthesized by the palladium-catalyzed Suzuki coupling reaction and it’s quaternized ammonium polyelectrolyte derivatives was obtained through a postpolymerization treatment on the terminal amino groups. The electrochemical and optical properties of the copolymers was fully investigated. The results showed that the new polyfluorene derivative had high electronic conductivity and strong fluorescence, therefore it had good potential to be used in chemical and biological sensors, as shown in optical sensing of bovine albumin (BSA) in this study.

A novel water-soluble polyfluorene derivative (P-2) was synthesized. P-2 showed good fluorescence performance which is beneficial to the application of P-2 for fluorescence sensor, we established a novel fluorescence probe-P-2 as a probe to determine BSA. The method has high sensitivity and simplicity of operation.Figure optionsDownload as PowerPoint slideHighlights
► A novel water-soluble polyfluorene derivative (P-2) was synthesized.
► P-2 is more suitable for biosensory systems in aqueous solution.
► Strong fluorescence enhanced sensitivity to oppositely charged quenchers BSA.
► Simplicity of operation, a novel luminescence probe.