Selective and sensitive spectrophotometric method for the determination of trace amounts of zirconium in environmental and biological samples using 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide

► A spectrophotometric method was proposed to determine zirconium in aqueous samples. ► The method was based on the complexation of zirconium and xipamide. ► It is a simple spectrophotometric, very sensitivity and low cost method. ► The important analytical parameters were investigated. ► The method was applied to the determination of Zr(IV) in environmental and biological samples.