Photoluminescence properties of sonochemically synthesized gold nanoparticles for DNA biosensing

The electronic interactions of sonochemically synthesized gold (Au) nanoparticles with AT- and GC-DNA were studied by measuring photoluminescence (PL) spectral properties and the inherent PL images of the Au nanoparticles incorporated with the single DNA molecules using a laser scanning confocal microscope. The Au-nanoparticles incorporated AT-DNA and GC-DNA exhibit confocal PL image. These results suggest a Lewis acid (Au)–Lewis base (N- or O-groups of DNA) type of interaction between Au nanoparticles and DNA.