کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1253334 1496296 2014 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Lipid metabolites with free-radical scavenging activity from Euphorbia helioscopia L.
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Lipid metabolites with free-radical scavenging activity from Euphorbia helioscopia L.
چکیده انگلیسی


• Bioassay oriented fractionation of methanolic extract of Euphorbia helioscopia L.
• Identification by spectroscopic data and chemical reactions of lipid metabolites.
• Identification of one active fraction from E. helioscopia L.
• FRS due to compound 10 with an Emax of 69% at 15 μg/mL (EC50 = 5.2 μg/mL).

The methanolic extract of the plant Euphorbia helioscopia L. exhibited an interesting free-radical scavenging activity.From the aerial parts of Euphorbia helioscopia L. (Euphorbiaceae), a complex mixture of seven cerebrosides together with glucoclionasterol, a digalactosyldiacylglycerol and a diacylmonogalactosylglycerol were identified. The structures of the cerebrosides were characterized as 1-O-β-d-glucosides of phytosphingosines, which comprised (2S, 3S, 4E, 8E)-2-amino-4(E),8(E)-octadecadiene-1,3-diol, (2S, 3S, 4E, 8Z)-2-amino-4(E),8(Z)-octadecadiene-1,3-diol, (2S, 3S, 4R, 8Z)-2-amino-8(Z)-octadecene-1,3,4-triol as long chain bases with seven 2-hydroxy fatty acids of varying chain lengths (C16, C24:1, C26:1, C24, C26, C28:1) linked to the amino group.The glycosylglycerides were characterized as (2S)-2,3-O-di-(9,12,15-octadecatrienoyl)-glyceryl-6-O-(α-d-galactopyranosyl)-β-d-galactopyranoside and (2S)-2,3-O-di-(9,12,15-octadecatrienoyl)-glyceryl-1-O-β-d-galactopyranoside. The structures were established on the basis of spectroscopic data and chemical reactions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemistry and Physics of Lipids - Volume 181, July 2014, Pages 90–98
نویسندگان
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