Antifungal and cytotoxic substances from the stem barks of Desmos chinensis

Isounonal-7-methyl ether (1) and chinendihydrochalcone (2) together with 8 known compounds were isolated from the stem barks of Desmos chinensis. Their structures were determined on the basis of spectroscopic data. Compound 2 exhibited cytotoxic activity against MOLT-3 cancer cell line (IC50 7.16 μg/mL) and antifungal activity against Pyricularia oryzae and Rhizoctonia solani with MIC values of 15.6 and 31.2 μg/mL, respectively.