High efficient probes with Schiff base functional receptors for hypochlorite sensing under physiological conditions

A series of novel and convenient fluorescent probes with Schiff base functionality were presented for direct detection of OCl−via the irreversible OCl−-promoted oxidation and hydrolyzation reaction in formation of the ring-opened product, fluorescein. Prominent high sensitivity, selectivity and anti-interference OCl−-induced fluorescence and color change over a wide range of tested metal ions performance were observed for each probe under physiological conditions, thus making the probes well suitable for sensing of OCl− in living cells.

A series of novel and convenient fluorescent probes with Schiff base functionality are presented for direct detection of OCl−via the irreversible OCl−-promoted oxidation and hydrolyzation reaction in the formation of the ring-opened product fluorescein. Prominent high sensitivity, selectivity and anti-interference performance were observed for each probe under physiological conditions, thus making the probes well suited for sensing of OCl− in living cells.Figure optionsDownload as PowerPoint slide