کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1256720 971527 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthetic receptors with antibody-like binding affinities
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Synthetic receptors with antibody-like binding affinities
چکیده انگلیسی

Antibodies are critical reagents in biological research and are increasingly being developed as therapeutic agents. They typically exhibit very high affinity and selectivity for their ligands. Synthetic protein-binding agents rarely achieve the combination of high affinity and selectivity for their target protein that is typical of a good antibody. However, significant efforts are underway to develop a new generation of protein ligands with improved properties. This article reviews progress towards this goal and suggests fruitful strategies for future research.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Chemical Biology - Volume 14, Issue 6, December 2010, Pages 713–720
نویسندگان
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