کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1256892 971535 2006 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nucleic acid aptamers and enzymes as sensors
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Nucleic acid aptamers and enzymes as sensors
چکیده انگلیسی

The function of nucleic acids has been an endless source of discovery and invention that has drastically enhanced our appreciation of DNA and RNA as multifaceted polymers. It is now widely known that nucleic acids can act as enzymes (deoxyribozymes and ribozymes) and as receptors (aptamers), and that these functional nucleic acids (FNAs) can either be found in nature or isolated from pools of random nucleic acids. The availability of many natural and artificial FNAs has opened a new horizon for the development of ‘smart’ molecules for a variety of chemical and biological applications. This review provides a snapshot of recent progress in the application of FNAs as novel sensors for biomolecular detection, drug discovery and nanotechnology.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Chemical Biology - Volume 10, Issue 3, June 2006, Pages 272–281
نویسندگان
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