کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1257263 971553 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sweet tasting chips: microarray-based analysis of glycans
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Sweet tasting chips: microarray-based analysis of glycans
چکیده انگلیسی

Glycosylation, a ubiquitous post-translational modification of proteins and lipids that generates enormous functional diversity, is rapidly gaining attention in the postgenomic era. The systematic study of glycans, that is glycomics, has been driven by the development of new analytical tools well suited to the inherent complexities of carbohydrate analysis, such as lectin-based microarray technologies. Recent work has demonstrated the utility of these analytical tools for glycomics in both clinical and research settings, for example identifying novel biomarkers associated with disease progression or studying HIV-1 exit mechanisms. This review highlights these new lectin-based microarray technologies and their role in the emerging field of glycomics.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Chemical Biology - Volume 13, Issue 4, October 2009, Pages 427–432
نویسندگان
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