کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1257697 | 971576 | 2011 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Apolipoprotein B100 analysis in microchip with electrochemical detection
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Apolipoprotein B100 analysis in microchip with electrochemical detection Apolipoprotein B100 analysis in microchip with electrochemical detection](/preview/png/1257697.png)
چکیده انگلیسی
Apolipoprotein B100 (apoB-100) is a major protein of the cholesterol-rich low-density lipoprotein (LDL) and reflects a better assessment of total atherogenic burden to the vascular system than LDL. In this work, a simple and sensitive method has been developed to determine picoliter apoB-100s using the PMMA microfluidic chip coupled with electrochemical detection system. This method performs very well with a detectable linear range of 1–800 pg/mL and a detection limit of 1 pg/mL. A real serum sample has further been detected by this microchip-based biosensor. The results show that this kind of method is practicable and has the potential application in clinical analysis and diagnosis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 22, Issue 11, November 2011, Pages 1343–1346
Journal: Chinese Chemical Letters - Volume 22, Issue 11, November 2011, Pages 1343–1346
نویسندگان
Cheng Cheng Liu, Yun Liu, Hui Xiang Wang, Yan Bo Qi, Peng Yuan Yang, Bao Hong Liu,