کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1259251 971669 2010 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Self-assembly of three-dimensional DNA nanostructures and potential biological applications
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Self-assembly of three-dimensional DNA nanostructures and potential biological applications
چکیده انگلیسی

A current challenge in nanoscience is to achieve controlled organization in three-dimensions, to provide tools for biophysics, molecular sensors, enzymatic cascades, drug delivery, tissue engineering, and device fabrication. DNA displays some of the most predictable and programmable interactions of any molecule, natural or synthetic. As a result, 3D-DNA nanostructures have emerged as promising tools for biology and materials science. In this review, strategies for 3D-DNA assembly are discussed. DNA cages, nanotubes, dendritic networks, and crystals are formed, with deliberate variation of their size, shape, persistence length, and porosities. They can exhibit dynamic character, allowing their selective switching with external stimuli. They can encapsulate and position materials into arbitrarily designed patterns, and show promise for numerous biological and materials applications.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Chemical Biology - Volume 14, Issue 5, October 2010, Pages 597–607
نویسندگان
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