کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1259373 1496497 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Glycomics and disease markers
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Glycomics and disease markers
چکیده انگلیسی

Glycomics is the comprehensive study of all glycans expressed in biological systems. The biosynthesis of glycan relies on a number of highly competitive processes involving glycosyl transferases. Glycosylation is therefore highly sensitive to the biochemical environment and has been implicated in many diseases including cancer. Recently, interest in profiling the glycome has increased owing to the potential of glycans for disease markers. In this regard, mass spectrometry is emerging as a powerful technique for profiling the glycome. Global glycan profiling of human serum based on mass spectrometry has already led to several potentially promising markers for several types of cancer and diseases.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Chemical Biology - Volume 13, Issues 5–6, December 2009, Pages 601–607
نویسندگان
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