کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1259873 971700 2010 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Near-infrared fluorescence: application to in vivo molecular imaging
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Near-infrared fluorescence: application to in vivo molecular imaging
چکیده انگلیسی

Molecular imaging often relies on the use of targeted and activatable reporters to quantitate and visualize targets, biological processes, and cells in vivo. The use of optical probes with near-infrared fluorescence allows for improved photon penetration through tissue and minimizes the effects of tissue autofluorescence. There are several parameters that define the effectiveness of imaging agents in vivo. These factors include probe targeting, activation, pharmacokinetics, biocompatibility, and photophysics. Recent advances in our understanding of these variables as they pertain to the application of optical reporters for in vivo imaging are discussed in this review.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Chemical Biology - Volume 14, Issue 1, February 2010, Pages 71–79
نویسندگان
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