Meat by-product is a Source of Tissue-specific Bioactive Proteins and Peptides against Cardio-vascular Diseases

The aim of the study was to investigate the functional properties of extracts and utrafiltrates prepared from pig aorta tissues using Guinea pigs with an experimental atherosclerosis model to determine the possibility of their implementation against cardiovascular disorders. Serum total cholesterol content, atherogenic index (AI), low density lipoproteins (LDL) and residual cholesterol (VLDL, IDL) reduction was noted (44.1%, 43.7%, 43.7% and 79.5%, respectively) in animals treated with low-molecular weight ultrafiltrate (LMU). Serum C-reactive protein (CRP) and Vascular endothelial growth factor (VEGF) concentrations declined by 34.0% and 58.3% on average, respectively in animals treated with LMU.