Self-assembled pentagonal bipyramidal and skew trapezoidal organotin(IV) complexes of substituted benzoic acids: Their antibacterial, antifungal, cytotoxic, insecticidal and urease inhibition activities

Fourteen di- and triorganotin(IV) derivatives with pentagonal bipyramidal and skew trapezoidal geometries have been synthesized and characterized. Dimethylstannyl bis[3-amino-4-chlorophenylcarboxylate] (1), bis[3-amino-4-chlorophenylcarboxylato] tetraethyldistannoxane] (2) and bis[3,5-dinitro-4-chlorophenylcarboxylato] tetra-n-butyldistannoxane (10) are dinuclear and tetranuclear complexes of bidentate ligands. The crystal structure of (1) is dimeric in which each Sn atom is seven coordinated. Study of weak intramolecular Sn⋯O interactions is very important to decide geometry around tin. Furthermore, it has been investigated that these compounds exhibit fairly good antibacterial, antifungal, cytotoxic, insecticidal and antiurease activities.

A series of new mononuclear, dinuclear and tetranuclear organotin(IV) derivatives of substituted benzoic acids have been synthesized and structurally characterized by various spectroscopic techniques and X-ray crystallography. The antibacterial, antifungal, cytotoxic, insecticidal and urease inhibition activities of these compounds have also been studied.Figure optionsDownload as PowerPoint slideResearch highlights
► Synthesis of pentagonal bipyramidal and skew trapezoidal organotin(IV) complexes.
► Weaker interactions affect the structure of these compounds in solid state.
► These interactions have been studied in solution state by multinuclear NMR spectroscopy.
► The compounds have shown fairly good biological activities.