Fluorescent primary sensor for zinc and resultant complex as secondary sensor towards phosphorylated biomolecules: INHIBIT logic gate

Imine linked “on–off” multi-responsive and selective chemosensor has been synthesized and evaluated for cation recognition properties. The receptor shows high sensitivity and selectivity for Zn2+ through changes in fluorescence intensity based on ESIPT and charge transfer (CT) mechanism. The Zn2+ complex of the receptor can be used for phosphate quantification and for recognition of phosphorylated biomolecules through cation displacement approach.

Imine linked “on–off” and selective chemosensor has been evaluated for cation recognition properties. The receptor shows sensitivity and selectivity for Zn2+ through ESIPT and charge transfer mechanism. The Zn2+ complex of the receptor can be used for phosphate quantification and recognition of phosphorylated biomolecules through cation displacement approach.Figure optionsDownload as PowerPoint slideHighlights
► Imine linked “on–off” and selective chemosensor has been developed.
► Receptor showed high sensitivity and selectivity for Zn2+ detection at μM level.
► Zn2+ complex of receptor can be used further for phosphate quantification.
► Phosphorylated biomolecules can be recognized through cation displacement approach.