Rhenium and technetium complexes with anionic or neutral scorpionates: An overview of their relevance in biomedical applications

This article reviews the chemistry of Re and Tc complexes anchored by anionic and neutral scorpionates with potential relevance in the field of biomedical applications, particularly in radiopharmaceutical research. For poly(azolyl)borates, the revised work focuses mainly on poly(mercaptoimidazolyl)borate tricarbonyl M(I) complexes, while for tris(pyrazolyl)methanes the revision includes M(VII) trioxo- and M(I) tricarbonyl complexes. A comprehensive update of structural, chemical, radiochemical and biological aspects relevant for the use of these compounds in the design of radiopharmaceuticals is presented and discussed.

A short and concise overview of Re and Tc complexes anchored by anionic or neutral scorpionates with relevance particularly in radiopharmaceutical research is presented. Structural, chemical, radiochemical and biological aspects of such complexes are discussed.Figure optionsDownload as PowerPoint slide