کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1311010 | 975273 | 2005 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: cis-Dichloroplatinum (II) complexes with aminomethylnicotinate and -isonicotinate ligands cis-Dichloroplatinum (II) complexes with aminomethylnicotinate and -isonicotinate ligands](/preview/png/1311010.png)
6-Aminomethylnicotinic acid (1a) and 2-aminomethylisonicotinic acid (1b) were each reacted with K2PtCl4 in aqueous 1 M HCl to give the corresponding N,N-chelated cis-dichloroplatinum(II) complexes 2. These were converted into amides 3 via their mixed anhydrides by treating them first with ethyl chloroformate and then with the respective 1° or 2° amine. The analogous 6-aminomethylnicotinic acid ester complexes 7 were obtained by reaction of the preformed ligands with K2PtCl4.
cis-Dichloro(6-aminomethylnicotinic acid)platinum (II) (2a) and cis-dichloro(2-aminomethyl-isonicotinic acid)platinum (II) (2b) were prepared from reaction of the free diamine ligands with K2PtCl4 in aqueous 1 M HCl. Complexes 2 were then converted to amide “conjugates” 3 by treating their mixed chloroformic acid anhydrides with the respective amines. The 6-amino-methylnicotinate complexes 7 were prepared by coordination of the preformed ligands 6.Figure optionsDownload as PowerPoint slide
Journal: Inorganica Chimica Acta - Volume 358, Issue 12, 1 August 2005, Pages 3369–3376