Synthesis of new chiral cis-3-aminoazetidines and their use in catalytic asymmetric reactions

A new series of chiral cis-3-aminoazetidines have been prepared from (S)-1-phenylethylamine. The catalytic activity of the new ligands has been tested in standard asymmetric reactions, in most cases moderate to good yields and moderate enantioselectivity have been observed.

A new series of chiral cis-3-aminoazetidines have been prepared from (S)-1-phenylethylamine. They exhibit moderate to good catalytic activities and moderate enantiomeric selectivities in most investigated asymmetric reactions.Figure optionsDownload as PowerPoint slide