کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1316801 976482 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Solution equilibrium characterization of insulin-mimetic Zn(II) complexes
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Solution equilibrium characterization of insulin-mimetic Zn(II) complexes
چکیده انگلیسی
Solution speciation (stoichiometry and stability constants) of the insulin mimetic Zn(II) complexes of several bidentate ligands with (O,O), (N,O) or (S,O) coordination modes have been determined by pH-metry at 25 °C and I = 0.2 M (KCl). All ligands were found to coordinate in a bidentate way forming mono, bis and tris complexes, besides a mixed hydroxo bis complex ZnL2(OH) detected in the slightly basic pH range together with the tris complex. Relationships between the stability data, lipophilicity of the complexes and earlier biological data are evaluated. The validity of the linear free energy relationships (LFER) between the proton and Zn(II) complexes and also between the VO(IV) and Zn(II) complexes is tested.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Inorganic Biochemistry - Volume 100, Issue 9, September 2006, Pages 1521-1526
نویسندگان
, , , , , ,